Acute cardiovascular shock,multi-organ failure,and death are sometimes not directly mediated by bacterial toxins but rather by:

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Quizplus · Accepted Answer

Acute cardiovascular shock, multi-organ failure, and death can be caused by excessive release of proinflammatory cytokines like TNF-alpha, IL-1, and IL-6, which can lead to a deadly cytokine storm. This is particularly true in sepsis and septic shock, where bacterial toxins can trigger an intense immune response that damages the host's own tissues and organs. Complement deficiency, hyperactive Th2 cells, and IL-10 are unlikely to be the primary causes of these severe clinical manifestations.

Acute Cardiovascular Shock,multi-Organ Failure,and Death Are Sometimes Not Directly Mediated