The C5 convertase of the classical pathway of complement activation is:

Question

Quizplus · Accepted Answer

The C5 convertase of the classical pathway of complement activation is C4b2a3b, which consists of a C4b molecule, a C2a molecule, and a C3b molecule. This complex is responsible for cleaving C5 into C5a and C5b, which initiates the formation of the membrane attack complex. Option A is the C3 convertase of the alternate pathway, option B is not a valid complex, and option D is the C3 convertase of the classical pathway.

The C5 Convertase of the Classical Pathway of Complement Activation