Kidney glomeruli can become obstructed with immune complexes as a result of:

Question

Quizplus · Accepted Answer

Inadequate C3b-mediated opsonization can lead to the accumulation of immune complexes in the kidney glomeruli, which can cause obstruction and lead to renal damage. Properdin deficiency (A) can increase susceptibility to infections but is not directly related to immune complex formation in the kidneys. Membrane attack complex formation (C) is a late step in the complement cascade and is not directly related to immune complex deposition in the kidneys. Autoantibodies that bind C3bBb (D) can lead to complement activation and tissue damage, but this process is not specific to the kidney glomeruli.

Kidney Glomeruli Can Become Obstructed with Immune Complexes as a Result