Which of the Following Is a Reason Why Transplanted Tissues

Which of the following is a reason why transplanted tissues and organs may be rejected by the host?

A) Host antibodies and cytotoxic T cells recognize foreign cytokines
B) Host antibodies and cytotoxic T cells recognize foreign histamines
C) Host antigens and plasma cells recognize foreign major histocompatibility complexes
D) Host antigens and plasma cells recognize foreign cytokines
E) Host antibodies and cytotoxic T cells recognize foreign major histocompatibility complexes