While Running a Marathon Over the Summer Kathy Cramped Up

While running a marathon over the summer Kathy cramped up and collapsed at mile 23.She could not continue because her legs were so cramped.Which of the following is the best explanation for why she couldn't continue her race?

A) During the race her quadriceps required large amounts of ATP.In order to supply this energy,cellular respiration was performed,using oxygen to break down glucose.As her oxygen levels dropped her body shifted to the fermentation pathway in which the glucose was converted into lactate.It is the build up of lactate that led to her leg muscles fatiguing and cramping.
B) During the race her biceps brachii required large amounts of ATP.In order to supply this energy,cellular respiration was performed,using oxygen to break down glucose.As her oxygen levels dropped her body shifted to the fermentation pathway in which the glucose was converted into lactate.It is the build up of lactate that led to her leg muscles fatiguing and cramping.
C) During the race her quadriceps required large amounts of ATP.In order to supply this energy,cellular respiration was performed,using oxygen to break down cellulose.As her oxygen levels dropped her body shifted to the fermentation pathway in which the glucose was converted into lactate.It is the build up of lactate that led to her leg muscles fatiguing and cramping.
D) During the race her quadriceps required large amounts of ADP.In order to supply this energy,cellular respiration was performed,breaking down glucose using carbon dioxide.As her oxygen levels dropped her body shifted to the fermentation pathway in which the glucose was converted into lactate.It is the build up of lactate that led to her leg muscles fatiguing and cramping.
E) During the race her pectoralis major required large amounts of ATP.In order to supply this energy,cellular respiration was performed,breaking down glucose using oxygen.As her oxygen levels dropped her body shifted to the fermentation pathway in which the glucose was converted into lactatE.It is the build up of lactate that led to her leg muscles fatiguing and cramping.