A disease characterized by hypoactivity of the thyroid with weight gain and a sluggish metabolism as a result of destruction of thyroglobulin best describes:

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The disease characterized by hypoactivity of the thyroid with weight gain and a sluggish metabolism as a result of destruction of thyroglobulin is Hashimoto's thyroiditis, an autoimmune disease that causes chronic inflammation and damage to the thyroid gland. Graves disease, on the other hand, is an autoimmune disease that causes hyperthyroidism (overactivity of the thyroid). Myasthenia gravis is a neuromuscular disorder that causes muscle weakness and fatigue. Rheumatoid arthritis is an autoimmune disease that primarily affects the joints.

A Disease Characterized by Hypoactivity of the Thyroid with Weight