To determine a patient's HLA type using the complement-dependent cytotoxicity test,which of the following must be used?

Question

Quizplus · Accepted Answer

The complement-dependent cytotoxicity test requires viable lymphocytes, which will react with the patient's serum and an antiserum from a commercial source to identify the individual's HLA type. The test works by the antiserum recognizing and binding to specific HLA antigens on the lymphocytes, which are then destroyed by complement-mediated lysis. The presence or absence of lysis indicates the patient's HLA type. Purified T cells or complement from patient serum are not required for this test.

To Determine a Patient's HLA Type Using the Complement-Dependent Cytotoxicity