Stevens-Johnson syndrome,in which the top layer of the skin dies and sheds,is caused by:

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Stevens-Johnson syndrome is commonly caused by certain medications or infections, including Mycoplasma pneumoniae. Streptococcus pyogenes can cause strep throat and skin infections, but is not a common cause of Stevens-Johnson syndrome. Rickettsia rickettsii causes Rocky Mountain spotted fever, and Helicobacter pylori is associated with gastrointestinal disorders, but neither are known to cause Stevens-Johnson syndrome.

Stevens-Johnson Syndrome,in Which the Top Layer of the Skin Dies