When developing clinical practice guidelines,what is the critical first step?

Question

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The critical first step in developing clinical practice guidelines is selecting and refining the topic upon which the investigation will center. This step involves identifying a clinical question or issue that is relevant to practice and for which there is uncertainty or variation in current practice. The topic should be selected by a panel of experts or a group of stakeholders, based on criteria such as the burden of the disease, the availability of evidence, and the potential impact of the guideline. Once the topic is selected, a systematic review of the literature is conducted to identify the best available evidence to answer the clinical question or address the issue. The other options may be important considerations in the guideline development process, but they are not the critical first step.

When Developing Clinical Practice Guidelines,what Is the Critical First Step