What component of an HPLC introduces an aliquot of sample into the column and how is this introduction accomplished with the high pressure in the flow path?

Question

Quizplus · Accepted Answer

A fixed-loop injector with a switching valve is typically used in HPLC to introduce an aliquot of sample into the column. This is accomplished by loading the sample into a fixed loop and then switching the valve to allow the sample to be injected into the flow path. The high pressure in the system helps to ensure that the sample is forced into the column and through the packing material for efficient separation. Options A, B, and C are not commonly used methods for introducing a sample into an HPLC column.

What Component of an HPLC Introduces an Aliquot of Sample