Some Analytes Must Be Derivatized to Increase Their Column Retention

Some analytes must be derivatized to increase their column retention or detectability.Derivatization means:

A) altering the chemical structure of the analyte to an isomeric form to increase detection and specificity.
B) adding fluorescent labels or combining the analyte with chiral reagents or other chemicals to increase detectability.
C) removing dissolved gases in the solvent to produce a clear chromatogram.
D) using multiple detectors to assist in identification.