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Statin Drugs Lower Cholesterol by Competitive Inhibition of the Cholesterol-Synthesizing

Question 19

Multiple Choice

Statin drugs lower cholesterol by competitive inhibition of the cholesterol-synthesizing enzyme HMG-CoA reductase.A competitive inhibitor binds:


A) the enzyme at a site other than the active center,thereby decreasing the Vmax of the reaction.
B) to the active center of the enzyme,with no effect on the Vmax of the reaction.
C) to the entire enzyme-substrate complex,thereby decreasing the Km.
D) to the active center of the enzyme,thereby causing the Km to increase.

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