One of the mutations that is found most frequently in cancers and can ultimately lead to colon cancer involves a:

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The most common mutation found in cancers that can lead to colon cancer is a point mutation in the K-ras proto-oncogene. This mutation prevents K-ras from being turned off and encourages the cell to continue dividing. The other choices, translocation of K-ras proto-oncogene to chromosome 14, frameshift mutation in the N-ras proto-oncogene, and large deletion in the N-ras proto-oncogene, are not commonly found mutations in colon cancer.

One of the Mutations That Is Found Most Frequently in Cancers