Metabolism of norepinephrine and epinephrine in adrenal chromaffin cells requires the presence of which one of the following enzymes for conversion into normetanephrine and metanephrine?

Question

Quizplus · Accepted Answer

The enzyme required for the conversion of norepinephrine and epinephrine into normetanephrine and metanephrine is catechol-O-methyltransferase. This enzyme adds a methyl group to the catechol ring of the molecules, leading to their inactivation and conversion into their respective metabolites. The other enzymes listed (dopamine-β-hydroxylase, tyrosine hydroxylase and monoamine oxidase) are involved in different steps of the synthesis and breakdown of catecholamines, but not in the specific conversion of norepinephrine and epinephrine to their metabolites.

Metabolism of Norepinephrine and Epinephrine in Adrenal Chromaffin Cells Requires β\betaβ

Metabolism of Norepinephrine and Epinephrine in Adrenal Chromaffin Cells Requires $\beta$