The rate-limiting step in the biosynthesis of catecholamines is the:
A) conversion of 3-methoxy-4-hydroxyphenylglycol (MHPG) to VMA by alcohol dehydrogenase.
B) conversion of tryptophan to 5-hydroxytryptophan by tryptophan hydroxylase.
C) metabolism by catechol-O-methyltransferase (COMT) to MHPG.
D) conversion of tyrosine to 3,4-dihydroxyphenylalanine by tyrosine hydroxylase.
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