In chronic liver failure,such as cirrhosis,there is a significant impairment of normal ammonia metabolism and eventual hyperammonemia.Elevated ammonia can lead to:

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Elevated ammonia levels can cause hepatic encephalopathy, a neurological condition characterized by confusion, lethargy, and eventually coma. Hepatic encephalopathy is a common complication of chronic liver failure, especially in advanced cirrhosis. Elevated ammonia levels can result from impaired liver metabolism of ammonia, as well as bacterial overgrowth in the gut, which produces ammonia as a byproduct of protein breakdown.

In Chronic Liver Failure,such as Cirrhosis,there Is a Significant Impairment