Hypercalcemia occurs in humoral hypercalcemia of malignancy (HHM) because:
A) tumors synthesize parathyroid hormone (PTH) ,which increases calcium levels in blood.
B) metastasizing cells synthesize calcium and release it into the circulation.
C) PTH-related protein (PTHrP) is synthesized by tumors and stimulates bone resorption.
D) osteoclasts bind tumor marker proteins and the process of bone remodeling becomes unregulated.
Correct Answer:
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