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A Woman with Thyroid Cancer Has Her Thyroglobulin (Tg)level Checked

Question 14

Multiple Choice

A woman with thyroid cancer has her thyroglobulin (Tg) level checked to assess return of thyroid function following surgery.The Tg value was markedly decreased.Her physician calls the laboratory asking for an explanation of the result.You respond that:


A) this is a typical value for someone with thyroid cancer and that Tg can be used as a tumor marker,so decreased values are better than increased values.
B) Tg is probably being interfered with by the immunoglobulins that are involved in the healing postsurgery process.
C) your laboratory uses a Tg assay that likely has been interfered with by Tg autoantibodies,which limits the accurate measurement of Tg.
D) thyroid cancer obliterates all colloid in the thyroid gland and therefore Tg will not be present in a blood sample.

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