Inhibin:

Question

Inhibin:

Quizplus · Accepted Answer

Inhibin inhibits the release of FSH from the male pituitary gland. It is produced by the Sertoli cells in response to FSH stimulation, and acts as a negative feedback signal to decrease FSH synthesis and secretion.

Answer: A and D (both are correct)
 Inhibin does not promote synthesis of testosterone by the Sertoli cells, but it does play a role in regulating FSH and LH secretion. Inhibin production is stimulated by elevated levels of GnRH, and it acts as a negative feedback signal to decrease FSH synthesis and secretion, while also decreasing the sensitivity of the pituitary gland to GnRH stimulation. However, in males, inhibin may also augment release of LH from the pituitary gland under certain conditions, such as during the early stages of puberty when the HPG axis is still developing.