When changes in virion structure occur as a result of major genetic changes,this is called

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Antigenic shift refers to the major genetic changes in a virus that result in changes to the virion structure, particularly the surface antigens. These changes can result in the virus being able to infect new hosts, evade immune system detection, or cause more severe disease. Antigenic drift, on the other hand, refers to smaller genetic changes that accumulate over time and can result in subtle changes to the surface antigens of a virus. Conformational mutagenesis is not a recognized term in virology. Mutational shift is not a common term used in virology, and could potentially be confused with antigenic shift.

When Changes in Virion Structure Occur as a Result of Major