Circulating T lymphocytes that have never before encountered antigen to which they are specific are referred to as

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Naive T cells are circulating lymphocytes that have not encountered their specific antigen before. They are activated upon recognition of their antigen by antigen-presenting cells, and they differentiate into effector cells or memory cells. Plasma cells, effector cells, and memory cells have already been exposed to their specific antigen. Antigen-presenting cells are cells that present antigen to T cells.

Circulating T Lymphocytes That Have Never Before Encountered Antigen to Which