The cellular basis for bacterial resistance to antimicrobics include
A)bacterial chromosomal mutations.
B)synthesis of enzymes that alter drug structure.
C)prevention of drug entry into the cell.
D)alteration of drug receptors on cell targets.
E)All of these choices are correct.

Question

Quizplus · Accepted Answer

All of the choices listed are mechanisms by which bacteria can develop resistance to antimicrobial agents. Bacterial chromosomal mutations can lead to changes in the target molecule that are not affected by the drug, synthesis of enzymes that can alter the drug structure can disable the drug, prevention of drug entry into the cell can prevent the drug from reaching the target, and alteration of drug receptors on cell targets can render the drug ineffective.

The Cellular Basis for Bacterial Resistance to Antimicrobics Include