The pathogenesis of rickettsial infections often involves infection of

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Rickettsial infections are often associated with the infection of the endothelial lining of blood vessels, leading to vasculitis and subsequent tissue damage. This can lead to a variety of clinical manifestations, including fever, rash, and multiorgan failure. In some cases, rickettsial infections may also involve other tissues or organs, but endothelial infection is a common feature.

The Pathogenesis of Rickettsial Infections Often Involves Infection of