Using mechanism of action,explain to a patient with lupus erythematosus how azathioprine (Imuran) works.
A) Azathioprine prevents the production of adenine and guanine, which are required for the production of deoxyribonucleic acid (DNA) and for cell growth and reproduction. Inhibition of DNA synthesis leads to the death of many existing lymphocytes and suppresses the formation of new B-cells and T-cells.
B) Azathioprine causes B-cell production of antibodies and killer T-cell activity.
C) Azathioprine stimulates the bone marrow to increase the production of macrophages and granulocytes.
D) None of these are correct
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