Explain what is meant by the statement "Griseofulvin is contraindicated in patients with acute intermittent porphyria."
A) Porphyria is a disease associated with insufficient liver production of delta aminolevulonic acid needed to metabolize the drug in the liver and characterized by intermittent hypertension, abdominal cramps, and psychosis which can be impacted by the fact that griseofulvin is extensively metabolized in the liver.
B) Porphyria is a disease associated with interference of the normal kidney function and characterized by intermittent hypertension and abdominal cramps, which can be impacted by the fact that griseofulvin is excreted mostly unchanged in the urine.
C) Porphyria is a disease associated with excessive liver production of delta aminolevulonic acid and characterized by intermittent hypertension, abdominal cramps, and psychosis which can be impacted by the fact that griseofulvin is extensively metabolized in the liver.
D) None of these are correct.
Correct Answer:
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