Use ACTH,cortisol,and 17-hydroxycorticosteroids to explain the process used in the diagnosis and treatment of Addison's disease.
A) ACTH is administered, and plasma levels of cortisol are measured. When the plasma level of this steroid does not rise or cannot be detected, primary adrenal failure, or Addison's disease, is present and short-term hormone replacement therapy must be started.
B) ACTH is administered and plasma levels of cortisol and 17-hydroxycorticosteroids (17-OHCS) are measured. When the plasma levels of these steroids do not rise or cannot be detected, primary adrenal failure, or Addison's disease, is present and short-term hormone replacement therapy must be started.
C) ACTH is administered and plasma levels of cortisol and 17-hydroxycorticosteroids (17-OHCS) are measured. When the plasma levels of these steroids do not rise or cannot be detected, primary adrenal failure, or Addison's disease, is present and chronic hormone replacement therapy must be started.
D) None of these are correct.
Correct Answer:
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