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Differentiate Between the Two Newest Laxative Products,Ceo-Two and Lubiprostone (Amitiza),and

Question 1

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Differentiate between the two newest laxative products,Ceo-Two and lubiprostone (Amitiza) ,and select the statement that best explains the mechanism of action of these agents.


A) Lubiprostone (Amitiza) releases carbon dioxide gas, which pushes on the wall of the rectum, inducing muscle contractions and stool movement. Ceo-Two opens the chloride channels so that chloride followed by water enters the channels in an attempt to maintain isotonic balance, accelerating transit time and stool softening.
B) Ceo-Two releases carbon dioxide gas, which pushes on the wall of the rectum, inducing muscle contractions and stool movement. Lubiprostone (Amitiza) opens the chloride channels so that chloride followed by water enters the channels in an attempt to maintain isotonic balance, accelerating transit time and stool softening.
C) Lubiprostone (Amitiza) and Ceo-Two open the chloride channels so that chloride followed by water enters the channels in an attempt to maintain isotonic balance, accelerating transit time and stool softening.
D) Ceo-Two releases carbon dioxide gas, which pushes on the wall of the rectum, inducing muscle contractions and stool movement. Lubiprostone (Amitiza) stimulates mu receptors in the myenteric plexus to decrease peristalsis, constrict sphincters, and directly affect the circular smooth muscle of the bowel, speeding gastrointestinal transit time.

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