Due to the potency of sodium and water removal by thiazide and thiazide-like diuretics,patients taking these diuretics may experience

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Because thiazide and thiazide-like diuretics rapidly remove water and sodium from the body, the plasma volume may decrease, causing a drop in blood pressure. Patients receiving these diuretics often experience orthostatic hypotension, which is a sudden drop in blood pressure when they quickly change from a sitting position to a standing position.

Due to the Potency of Sodium and Water Removal by Thiazide