Using the Physiological Effects of the Injected Benzodiazepine and Barbiturate

Using the physiological effects of the injected benzodiazepine and barbiturate anesthetic agents on the respiratory system,select the true statement.

A) Benzodiazepines and barbiturates produce a dose-dependent respiratory depression.
B) Benzodiazepines and barbiturates decrease respiratory rate and tidal volume.
C) Patients with underlying chronic obstructive pulmonary disease are more susceptible to respiratory depression from the use of benzodiazepine and barbiturate anesthetic agents, even at doses that would be considered therapeutic in healthy individuals.
D) All of these are correct.