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Differentiate Between the Tricyclic and Bicyclic Antidepressants,and Select the Correct

Question 21

Multiple Choice

Differentiate between the tricyclic and bicyclic antidepressants,and select the correct statement.


A) The tricyclics are referred to as tertiary amines because they contain three amine substitutions on the nitrogen in the chemical structure.
B) The bicyclics are referred to as secondary amines because they contain two amine substitutions on the nitrogen in the chemical structure.
C) Secondary amines mainly increase brain levels of norepinephrine more than serotonin, while the tertiary amines increase brain levels of serotonin more than epinephrine.
D) All of these are correct.

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