Select the statement that is not consistent with the mechanism of action or adverse effect profiles of the atypical SSRIs nefazodone (Serzone) and trazodone (Desyrel).

Question

Quizplus · Accepted Answer

Nefazodone (Serzone) and trazodone (Desyrel) are drugs that are weak reuptake inhibitors of serotonin and norepinephrine but potent antagonists of serotonin 5HT_2A receptors. This action also provides some antipsychotic activity. Adverse effects include sedation, orthostatic hypotension, and liver toxicity. Trazodone also is associated with priapism, which is the development of sustained and painful penile erections.

Select the Statement That Is Not Consistent with the Mechanism