In Large Doses,barbiturates Lead to Cardiovascular and Central Nervous System

In large doses,barbiturates lead to cardiovascular and central nervous system depression.Use critical thinking to select the reason this depression occurs.

A) Reduced activity in the medulla oblongata increases sympathetic control of the blood vessels, leading to hypertension, kidney failure, and irregular breathing.
B) Increased activity in the medulla oblongata decreases sympathetic control of the blood vessels, leading to hypotension, kidney failure, and irregular breathing.
C) Reduced activity in the medulla oblongata removes sympathetic control of the blood vessels, leading to hypotension, kidney failure, irregular breathing, and hypoxia.
D) None of these are correct.