Logan is diagnosed with rheumatoid arthritis.He is prescribed a drug that is to be taken orally.Logan is informed by his doctor that the drug has a half-life of 15 days.He also explains that he may experience diarrhea.Which of the following drugs has Logan been prescribed?

Question

Quizplus · Accepted Answer

Logan has been prescribed leflunomide (Arava). Leflunomide is currently used in the treatment of rheumatoid arthritis. The drug is converted to a long-acting metabolite that inhibits the synthesis of pyrimidines and DNA. This action inhibits the proliferation of both T-cells and B-cells involved in rheumatoid arthritis. Leflunomide is taken orally and has a half-life (on average) of 15 days.

Logan Is Diagnosed with Rheumatoid Arthritis