A leukemia patient is currently not responding to cyclophosphamide despite having favorable results with the drug in the past.The patient is most likely to have developed a problem in his _____.

Question

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Cyclophosphamide is one of the most important and frequently used alkylating drugs. The drug is metabolized in the liver to phosphoramide mustard, which is the active metabolite that produces alkylation.

A Leukemia Patient Is Currently Not Responding to Cyclophosphamide Despite