The Suppression of Acid Secretion Is Greater with a Proton

The suppression of acid secretion is greater with a proton pump inhibitor than with an H₂-receptor antagonist because:

A) unlike an H₂-receptor antagonist, a proton pump inhibitor blocks the secretion of HCl.
B) unlike an H₂-receptor antagonist, a proton pump inhibitor blocks the release of histamine from parietal cells.
C) unlike an H₂-receptor antagonist, a proton pump inhibitor increases the volume and strength of acid secretion.
D) unlike an H₂-receptor antagonist, a proton pump inhibitor stimulates H₁-receptors.