Select the Primary Reason Why the Preferred Route of Administration

Select the primary reason why the preferred route of administration for the corticosteroids in the treatment of chronic asthma and COPD is oral inhalation with metered-dose inhalers.

A) The advantage of inhalation is that lower dosages of steroid are delivered directly into the respiratory tract, therefore limiting systemic absorption and the adverse effects associated with steroid use.
B) The advantage of inhalation is that it prevents the abnormal increase in liver enzymes and the development of fever, dark urine, clay-colored stools, or jaundice.
C) The advantage of inhalation is that it prevents sleep disorders and suicidal ideation.
D) None of these are correct.