Identify the physiologic action that results from the administration of venodilators such as nitroglycerin and isosorbide dinitrate.

Question

Quizplus · Accepted Answer

Nitrate drugs such as nitroglycerine and isosorbide dinitrate primarily cause venodilation, especially of the larger veins and vena cava. When the heart is congested and overloaded with blood, the contractile force is greatly reduced. Venodilators reduce venous return and preload. The amount of blood returning to the heart is decreased, which allows the heart to pump more forcefully to increase cardiac output.

Identify the Physiologic Action That Results from the Administration of Venodilators