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Select the Statement That Is Consistent with the Mechanism of Action

Question 11

Multiple Choice

Select the statement that is consistent with the mechanism of action of phenytoin (Dilantin) that helps decrease the occurrence of a seizure.


A) Phenytoin prolongs the inactivation period of sodium (Na+) channels in the nerve membrane, leading to a reduction in the generation of high-frequency repetitive firing of action potentials from neurons involved in initiating seizures.
B) Phenytoin decreases the inhibitory effects of the inhibitory neurotransmitter gammaaminobutyric acid (GABA) , which suppresses the excitability of epileptogenic neurons.
C) Phenytoin decreases the inactivation of Na+ ion channels to decrease high-frequency firing of neurons and inhibition of Ca ++ ion channels.
D) None of the above are correct.

Correct Answer:

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