Select the statement that is consistent with the mechanism of action of phenytoin (Dilantin) that helps decrease the occurrence of a seizure.
A) Phenytoin prolongs the inactivation period of sodium (Na+) channels in the nerve membrane, leading to a reduction in the generation of high-frequency repetitive firing of action potentials from neurons involved in initiating seizures.
B) Phenytoin decreases the inhibitory effects of the inhibitory neurotransmitter gammaaminobutyric acid (GABA) , which suppresses the excitability of epileptogenic neurons.
C) Phenytoin decreases the inactivation of Na+ ion channels to decrease high-frequency firing of neurons and inhibition of Ca ++ ion channels.
D) None of the above are correct.
Correct Answer:
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