Identify the possible cause of nausea, vomiting, and headache that an alcoholic patient is experiencing while taking disulfiram.

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Disulfiram slows the conversion of acetaldehyde to acetyl coenzyme A. Therefore, acetaldehyde accumulates in the blood, producing nausea, vomiting, headache, and hypotension. This is known as a disulfiram reaction. Patients taking disulfiram are instructed not to ingest any alcoholic beverages, including cough syrups, special wine sauces, and fermented beverages (cider).

Identify the Possible Cause of Nausea, Vomiting, and Headache That