Ella has been taking large doses of a particular neuromuscular blocker over a very long period of time.Consequently,she has developed signs of respiratory paralysis and has severe trouble breathing.After Dr.Kurt examines her,he concludes that Ella's deteriorating health is the result of the growing concentration of the neuromuscular blocker drug in her system.He prescribes the drug neostigmine to relieve her symptoms.How will the drug neostigmine help counteract the effects of the neuromuscular blocker drug?

Question

Quizplus · Accepted Answer

Skeletal muscle paralysis caused by the nondepolarizing blockers may be reversed by the use of neostigmine or edrophonium. Neostigmine and edrophonium inhibit acetylcholinesterase so that ACH accumulates within the junctions. The ACH displaces the blocker from the nicotinic-muscle receptors and, since their receptors are not damaged or changed, initiates depolarization and muscle contraction.

Ella Has Been Taking Large Doses of a Particular Neuromuscular