Which factor is most likely responsible for the variation of duration of action in nondepolarizing skeletal muscle relaxants?

Question

Quizplus · Accepted Answer

As a class, nondepolarizing skeletal muscle relaxants are not similar in where and how they are metabolized before being excreted. Rocuronium is metabolized in the liver and cisatracurium is spontaneously degraded in the plasma. The duration of action, therefore, varies with the type of metabolism the drug undergoes.

Which Factor Is Most Likely Responsible for the Variation of Duration