How Would John,an Elderly Patient Who Smokes and Consumes Alcohol,tolerate

How would John,an elderly patient who smokes and consumes alcohol,tolerate an adult-strength dose of actively oxidized medication in comparison to Rick,an elderly patient who neither smokes nor drinks?

A) John would not be able to metabolize the drug, whereas Rick would be able to metabolize it.
B) Rick would be able to metabolize the drug in the same amount of time as John would be able to metabolize it.
C) John would be able to metabolize the drug at a faster rate than Rick would be able to metabolize it.
D) Rick's body would absorb a lesser amount of the drug than John's body would absorb.