Use a half-life of 8 hours to determine the amount of a drug left in the body at 4 p.m.if a 500-mg dose of the drug was taken at 8 a.m.

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The half-life of a drug is the time required for the blood or plasma concentration of the drug to fall to half of its original level. The number of hours that have lapsed between 8 a.m. and 4 p.m. is 8 hours. The half-life of the drug is 8 hours; this implies that one half-life has elapsed since the administration of the drug. The amount of the drug remaining at 4 p.m. is 50 percent of its initial dose (50% F1F1F1S1F1F1F10 500 mg = 250 mg).

Use a Half-Life of 8 Hours to Determine the Amount