Three medications have the following therapeutic index values: 2,4,and 0.5.Which medication is the safest?

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The therapeutic index (TI) is a ratio of the lethal dose 50 (LD50) to the effective dose 50 (ED50) of a drug. A therapeutic index value of four indicates that four times as much drug is needed to produce a lethal effect in 50 percent of the animals as is needed to produce the therapeutic effect in 50 percent of the animals.

Three Medications Have the Following Therapeutic Index Values: 2,4,and 0