Daily Co-Administration of Both Aspirin and Ibuprofen Can _____ the Overall

Daily co-administration of both aspirin and ibuprofen can _____ the overall antiplatelet effects of aspirin because _____.

A) cancel; ibuprofen is a COX-1 inhibitor and can occupy the same enzymatic site in the platelets but does not have the ability to alter the active site on COX or inhibit thromboxane production
B) increase; ibuprofen is a COX-1 enhancer and has the ability to alter the active site on COX and inhibit thromboxane production
C) delay; aspirin interferes with ibuprofen's inactivation of COX-1 enzyme
D) have no effect on; ibuprofen seldom interferes with platelet aggregation