Cholera is a bacterial disease, in which fatal dehydration can occur due to loss of water into the intestines. Cystic fibrosis is a human genetic disease characterized by excess mucus buildup on the linings of the lungs, making breathing difficult. Cholera acts on intestine cells to force water transport out of the cells and the body. Cystic fibrosis has an abnormal CFTR transport protein that limits water transport out of the cells and the body.
-What hypothesis was tested by researcher Sherif Gabriel and his colleagues?

Question

Cholera is a bacterial disease, in which fatal dehydration can occur due to loss of water into the intestines.  Cystic fibrosis is a human genetic disease characterized by excess mucus buildup on the linings of the lungs, making breathing difficult. Cholera acts on intestine cells to force water transport out of the cells and the body. Cystic fibrosis has an abnormal CFTR transport protein that limits water transport out of the cells and the body.
-What hypothesis was tested by researcher Sherif Gabriel and his colleagues?

Quizplus · Accepted Answer

Sherif Gabriel and his colleagues likely tested the hypothesis that defective CFTR, which is characteristic of cystic fibrosis, gives people natural resistance to cholera. This is because both conditions involve the regulation of water transport in the body, but in opposite ways.

Cholera Is a Bacterial Disease, in Which Fatal Dehydration Can