In the absence of growth factors,the retinoblastoma (RB) protein binds a transcription activator called E2F,preventing the cell from entering S stage.A mutation in E2F occurs that causes RB to no longer bind it.This mutant E2F would be considered a(n)
A) oncogene.
B) proto-oncogene.
C) tumor supressor.
D) gain-of-function mutant.
E) growth factor.
Correct Answer:
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