The enzyme that converts pyruvic acid into acetyl CoA requires vitamin B₁,also called thiamine.Vitamin B₁ has to be taken in through the diet of an individual.At what phase would cellular respiration come to a halt without B₁?

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The preparatory reaction, also known as the link reaction, involves the conversion of pyruvic acid to acetyl CoA, which requires the enzyme pyruvate dehydrogenase. This enzyme needs thiamine (vitamin B1) as a cofactor. Without vitamin B1, this conversion cannot occur, halting cellular respiration at this stage.

The Enzyme That Converts Pyruvic Acid into Acetyl CoA Requires