What Evidence Contributed to the Formulation of the RNA-First Hypothesis

What evidence contributed to the formulation of the RNA-first hypothesis?

A) RNA was formed in MIller's experiment.
B) RNA continues to evolve chemically today.
C) More primitive cells, such as archaea, use an RNA only information system.
D) RNA can sometimes be both a substrate and an enzyme during RNA processing.
E) Protocells contain only RNA and lipids.