The juxtaglomerular apparatus regulates the filtration rate by ________.
A)vasodilation of the peritubular capillaries
B)vasoconstriction of the peritubular capillaries
C)renin-angiotensin II vasoconstricting both the afferent and efferent arterioles
D)increasing osmotic pressure in the glomerular capsule

Question

Quizplus · Accepted Answer

The juxtaglomerular apparatus consists of three cells types: macula densa cells, granular cells, and extraglomerular mesangial cells. Granular cells release the enzyme renin in response to decreased blood pressure or volume, low sodium levels, or sympathetic nervous system activation. Renin then catalyzes the conversion of angiotensinogen to angiotensin I, which is converted to angiotensin II by the action of angiotensin-converting enzyme (ACE). Angiotensin II is a potent vasoconstrictor and causes vasoconstriction of both the afferent and efferent arterioles, ultimately increasing the filtration rate.

The Juxtaglomerular Apparatus Regulates the Filtration Rate by ________